Op.Dr. Nurettin Türktekin
Genetics and In Vitro Fertilization

Genetics and In Vitro Fertilization

The Relationship Between Genetics and IVF Success

In vitro fertilization method is the fertilization of egg cells taken from the woman and sperm taken from the man in a laboratory environment.

The embryo resulting from this process is placed in the uterus of the expectant mother with a method called embryo transfer. The Beta HCG level in the expectant mother's blood is checked with a blood test performed two weeks later. In this way, it becomes clear whether the expectant mother has become pregnant through the genetic in vitro fertilization method.

What is the Relationship Between Genetics and IVF?

In vitro fertilization treatment (IVF) is the process of removing eggs from mature ovaries and fertilizing them by sperm in a laboratory environment. These steps are sometimes divided into different sections and the treatment process may take longer. Genetic engineering is constantly making improvements to provide more successful results with in vitro fertilization studies. In this method, egg cells produced in the female body are removed from the body using special needles.

In vitro fertilization is the most effective type of assisted reproductive technology that has been used since the late 1970s. The question of whether female infertility is genetic is frequently asked in research on such treatments. This method, called IVF, can be applied to individuals with various fertility-related problems to have children.

What are the Symptoms of In Vitro Fertilization Treatment?

The question of whether male infertility is genetic comes to the fore in in vitro fertilization applications. This treatment method provides a solution to not only women but also men having problems in fertilizing eggs. The egg and sperm brought together in the laboratory environment are fertilized and form an embryo. Age, ovarian reserve, blood hormone values and height and weight status are important in people who will undergo in vitro fertilization treatment. When these criteria are taken into consideration, the probability of treatment success increases.

This embryo, which is placed in the uterus of the expectant mother, is examined 2 weeks after its development. If the blood test is positive, it means pregnancy has occurred. In addition, back pain, abdominal pain, nausea and spotting are observed in expectant mothers undergoing in vitro fertilization treatment. After the patient menstruates, hormone therapy is started to ensure egg development for an average of 8-10 days.

Who is a Suitable Candidate for In Vitro Fertilization Treatment?

First of all, in couples who have difficulty in having children, the source of the problem should be determined by a detailed examination. The method that will enable the couple to have a baby in the easiest and healthiest way should be determined. Genetic screening in in vitro fertilization treatment is an important procedure to understand whether the treatment is successful or not. People who have trouble getting pregnant for various reasons can take a screening test. Male patients who have no sperm in their semen are subjected to surgery.

For expectant mothers and fathers who meet the appropriate conditions, treatment begins by ensuring egg development with medications. If sperm cannot be obtained as a result of genetic testing, in vitro fertilization treatment cannot be performed. Similarly, women who have lost their ovulation function, that is, their egg reserve has run out, cannot benefit from this treatment. In addition, in vitro fertilization treatment cannot be applied because women in menopause cannot achieve pregnancy.

How is the IVF Treatment Procedure Done?

If pregnancy does not occur despite spouses having unprotected and regular sexual intercourse for a year, they should consult a doctor. Expectant mothers and fathers are first examined and subjected to some tests during in vitro fertilization treatment. After this, the following stages are applied in genetic in vitro fertilization treatment:

  • Ovulation induction (stimulation of eggs)
    collection of eggs
  • Ensuring fertilization by microinjection method (ICSI) or classical in vitro fertilization method (IVF)
  • Transferring embryos to the expectant mother
    pregnancy checks

The solution for couples who cannot have a baby for any reason is in vitro fertilization. It is performed by fertilizing eggs and sperm taken from men and women through medical interventions. If the pregnancy process has started at the end of these 5 stages, the expectant mother is called for ultrasound checks within 7 days. Since the first 3 months of pregnancy are very important, it is recommended to listen to the instructions given by the doctor during this period. In order to avoid any problems during the in vitro fertilization treatment stages, doctors who are experienced in this field should be selected.

What Happens During the Recovery Process After IVF Treatment?

Developments in genetic science have also improved in vitro fertilization treatment since the 1970s. During this process, the medications prescribed by the doctor must be used without interruption. Because it is very important for healthy embryos to adhere to the inner lining of the uterus during the in vitro fertilization transfer process. Medicines that increase the chance of pregnancy must be used regularly to ensure this retention. Those who have in vitro fertilization should pay attention to the following points during the recovery process:

  • Heavy sports exercises should not be done for the first few days after treatment.
  • Paints and liquids containing lead should be avoided.
  • Heavy loads should not be carried.
  • It is not right to swim because of the risk of vaginal infection.
  • Cigarettes and alcohol should not be consumed.
    two weeks of sexual intercourse



Ovarian cysts are fluid-filled sacs or vesicles seen inside the ovary. Normally, during each menstrual period, a cyst called a follicle, which carries the egg cell and can reach 3 cm in size, forms in the ovaries. Then this cyst cracks and the egg is released. In young girls with ovulation problems, normal or physiological follicle cysts that cannot rupture can grow every month and reach 5-10 cm, while small numbers of 0.5-1 cm in size, which we call polycystic ovaries, can be seen in series. Apart from these functional cysts, benign or malignant ovarian cysts can also be seen in all age groups.

Except for the most common functional ovarian cysts, cysts can be benign or malignant tumoral cysts. In addition, as a result of infection, abscess-shaped cysts may occur, which is usually accompanied by pain and high fever.


Embryo genetic testing or preimplantation genetic diagnosis (PGD) is performed when one or both parents who want to have a child have an inherited genetic disorder. This type of genetic disorder is performed in order for couples to have healthy embryos. By looking at the genetic characteristics of the embryos, it can be observed whether they carry genetic diseases and whether they will form a healthy pregnancy.

In embryo genetic screening tests, the genetic health of the fetus or embryo is examined. Certain genetic diseases or chromosomal abnormalities are detected. Within the scope of these tests, details such as chromosome number, genetic diseases, and sex determination can be examined. With embryo genetic tests applied in IVF treatment, the number, structure, and shape of genes are examined.

Genetic tests to be applied for the embryo do not harm. PGD or biopsy procedures can be applied harmlessly. As a result of the tests, healthy embryos are transferred to the womb of the expectant mother. By determining the health of the embryo, the chance of IVF success and healthy pregnancy are provided. Healthy embryos suitable for embryo transfer can be selected in this way. The risk of miscarriage and other risks can also be prevented in this way.

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